The Basic Principles Of sok
The function of SIK1 in tumorigenesis. SIK1 is usually a tumor suppressor gene, which performs a vital regulatory role in GNAS, KRAS mutation and LKB1 deletion mediated tumors. SIK1 inhibits CREB mediated transcription and affects cancer mobile proliferation, metabolic reprogramming and inflammatory microenvironment. SIK1 also can encourage most ca